ROCK inhibitor Glycyl-H 1152 2HCl, Purity ≥98%

Synonym: 913844-45-8; Rho kinase inhibitor IV; ROCK inhibitor

Product Size

1 mg; 2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Glycyl-H 1152 2HCl blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets Aurora A, CaMK II, PKG, and ROCKII.

Molecular Weight

449.4

Molecular Formula

C₁₈H₂₄N₄O₃S.2HCl

Targets

Aurora A: 2.35 μM; CaMK II: 2.57 μM; PKG: 3.26 μM; ROCKII: 11.8 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

Glycyl-H 1152 2HCl is used to study the inhibition of Rho-associated protein kinases in cell motility research.