ROCK inhibitor H-1152 dihydrochloride, Purity ≥98%

Synonym: 871543-07-6; H 1152 dihydrochloride; H1152 dihydrochloride; ROCK inhibitor

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

H-1152 dihydrochloride blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets Abl, AMPK, AuroraA, and CaMKII.

Molecular Weight

392.34

Molecular Formula

C₁₆H₂₃Cl₂N₃O₂S

Targets

Abl: 7.77 μM; AMPK: 100 μM; AuroraA: 0.745 μM; CaMKII: 0.18 μM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

H-1152 dihydrochloride is used to explore its selective inhibition of Rho-kinase in cell migration and proliferation studies.