ROCK inhibitor H-1152, Purity ≥98%

Synonym: 451462-58-1; H 1152; H1152; ROCK inhibitor

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

H-1152 blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets Abl, AMPK, AuroraA, and CaMKII.

Molecular Weight

319.42

Molecular Formula

C₁₆H₂₁N₃O₂S

Targets

Abl: 7.77 μM; AMPK: 100 μM; AuroraA: 0.745 μM; CaMKII: 0.18 μM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

H-1152 is utilized to study its inhibitory effects on Rho-kinase in cellular contractility research.

Storage

Store at -20ºC.