ROCK inhibitor Hydroxyfasudil hydrochloride, Purity ≥98%

Synonym: 155558-32-0; HA-1100 hydrochloride; HA 1100 hydrochloride; HA1100 hydrochloride; ROCK inhibitor

CAS Number: 155558-32-0
Compound CID: 11371328

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxyfasudil hydrochloride, soluble in warmed DMSO and warmed water and insoluble in ethanol, blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets PKA, ROCK1, and ROCK2.

Molecular Weight

343.83

Molecular Formula

C₁₄H₁₈ClN₃O₃S

Targets

PKA: 37 μM; ROCK1: 0.73 μM; ROCK2: 0.72 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 67 mg/mL (194.86 mM); Warmed water: 59 mg/mL (171.59 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Hydroxyfasudil hydrochloride can be used to investigate the inhibition of Rho kinase and its potential therapeutic effects.

Storage

Store at -20ºC.