ROCK inhibitor Hydroxyfasudil hydrochloride, Purity ≥98%

Synonym: 155558-32-0; HA-1100 hydrochloride; HA 1100 hydrochloride; HA1100 hydrochloride; ROCK inhibitor

CAS Number: 155558-32-0
Compound CID: 11371328

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxyfasudil hydrochloride, soluble in warmed DMSO and warmed water and insoluble in ethanol, blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets PKA, ROCK1, and ROCK2.

Molecular Weight

343.83

Molecular Formula

C₁₄H₁₈ClN₃O₃S

Targets

PKA: 37 μM; ROCK1: 0.73 μM; ROCK2: 0.72 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 67 mg/mL (194.86 mM); Warmed water: 59 mg/mL (171.59 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Hydroxyfasudil hydrochloride can be used to investigate the inhibition of Rho kinase and its potential therapeutic effects.