Properties
Description
Hydroxyfasudil blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets PKA, ROCK1, and ROCK2.
Molecular Formula
C14H17N3O3S
Targets
PKA: 37 μM; ROCK1: 0.73 μM; ROCK2: 0.72 μM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Hydroxyfasudil can be used to study inhibition of Rho kinase for therapeutic applications in cardiovascular diseases.
