ROCK inhibitor Rho-Kinase-IN-1, Purity ≥98%

Synonym: 1035094-83-7; Rho-Kinase-IN-1; N-[1-[(4-methylsulfanylphenyl)methyl]piperidin-3-yl]-1H-indazol-5-amine; SCHEMBL657506; CHEMBL3689352; ROCK inhibitor

CAS Number: 1035094-83-7
Compound CID: 25008330

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Rho-Kinase-IN-1 blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK1 and ROCK2.

Molecular Weight

352.5

Molecular Formula

C₂₀H₂₄N₄S

Targets

ROCK1: 30.5 nM (Ki); ROCK2: 3.9 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Rho-Kinase-IN-1 can be used to study inhibition of Rho kinase in cardiovascular and neurological diseases.

Storage

Store at -20ºC.