ROCK inhibitor ROCK inhibitor, Purity ≥98%

Synonym: 867017-68-3; Rho-kinase inhibitor; Rho kinase inhibitor; ROCK; ROCK inhibitor

CAS Number: 867017-68-3
Compound CID: 11524200

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ROCK inhibitor, soluble in DMSO and ethanol and insoluble in water, blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets FLT3, ROCK-1, ROCK-2, and TRK.

Molecular Weight

402.79

Molecular Formula

C₁₈H₁₃ClF₂N₆O

Targets

FLT3: 303 nM; ROCK-1: 0.6 nM; ROCK-2: 1.1 nM; TRK: 252 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 77 mg/mL (191.16 mM); Water: Insoluble; Ethanol: 2 mg/mL (4.96 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

ROCK inhibitor can be employed to research its effects on inhibiting Rho-associated protein kinases in various physiological and pathological processes.