Properties
Description
SAR407899 HCl blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK-1 and ROCK-2.
Molecular Formula
C14H17ClN2O2
Targets
ROCK-1: 276 nM; ROCK-2: 102 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
SAR407899 HCl can be used to investigate selective inhibition of ROCK2 in cardiovascular research.