Properties
Description
SAR407899 HCl blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK-1 and ROCK-2.
Molecular Formula
C14H17ClN2O2
Targets
ROCK-1: 276 nM; ROCK-2: 102 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
SAR407899 HCl can be used to investigate selective inhibition of ROCK2 in cardiovascular research.