Properties
Description
SB-772077B dihydrochloride blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK1 and ROCK2.
Molecular Formula
C15H20Cl2N8O2
Targets
ROCK1: 5.6 nM; ROCK2: 6 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
SB-772077B dihydrochloride can be used to research ROCK inhibition in various disease models.