ROCK inhibitor SLx-2119, Purity ≥98%

Synonym: 911417-87-3; SLx 2119; SLx2119; ROCK inhibitor; KD-025; KD025; ROCK inhibitor

CAS Number: 911417-87-3
Compound CID: 11950170

Product Size

5 mg; 10 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SLx-2119, soluble in DMSO and insoluble in ethanol and water, blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK2 and ROCK2.

Molecular Weight

452.51

Molecular Formula

C₂₆H₂₄N₆O₂

Targets

ROCK2: 60 nM; ROCK2: 41 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 84 mg/mL (185.63 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

SLx-2119 can be used to study the inhibition of ROCK2 for potential therapeutic effects in fibrosis and inflammation.