ROCK inhibitor SR 3677 dihydrochloride, Purity ≥98%

Synonym: 1072959-67-1; SR3677; SR-3677; ROCK inhibitor

Product Size

10 mg; 25 mg; 50 mg; 100mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SR 3677 dihydrochloride blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK-I and ROCK-II.

Molecular Weight

481.37

Molecular Formula

C₂₂H₂₄N₄O₄.2HCl

Targets

ROCK-I: 56 nM; ROCK-II: 3 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SR 3677 dihydrochloride is employed to study its selective inhibition of ROCK2 in cell signaling.

Storage

Store at -20ºC.