ROCK inhibitor Thiazovivin, Purity ≥98%

Synonym: Thiazovivin; 1226056-71-8; N-benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide; Thiazovivin (GMP); N-benzyl-2-(pyrimidin-4-ylamino)-1,3-thiazole-4-carboxamide; N-Benzyl-2-(pyrimidin-4-ylamino)-thiazole-4-carboxamide; N-(PHENYLMETHYL)-2-(4-PYRIMIDINYLAMINO)-4-THIAZOLECARBOXAMIDE; ROCK inhibitor

MDL: MFCD16495823
CAS Number: 1226056-71-8
Compound CID: 46209426

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Thiazovivin, soluble in DMSO and insoluble in ethanol and water, blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK.

Molecular Weight

311.4

Molecular Formula

C₁₅H₁₃N₅OS

Targets

ROCK: 0.5 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 15 mg/mL (48.17 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Thiazovivin can be used to enhance the reprogramming of somatic cells to induced pluripotent stem cells and study its effects on cell adhesion.