ROCK inhibitor Thiazovivin, Purity ≥98%

Synonym: Thiazovivin; 1226056-71-8; N-benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide; Thiazovivin (GMP); N-benzyl-2-(pyrimidin-4-ylamino)-1,3-thiazole-4-carboxamide; N-Benzyl-2-(pyrimidin-4-ylamino)-thiazole-4-carboxamide; N-(PHENYLMETHYL)-2-(4-PYRIMIDINYLAMINO)-4-THIAZOLECARBOXAMIDE; ROCK inhibitor

MDL: MFCD16495823
CAS Number: 1226056-71-8
Compound CID: 46209426

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Thiazovivin, soluble in DMSO and insoluble in ethanol and water, blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK.

Molecular Weight

311.4

Molecular Formula

C₁₅H₁₃N₅OS

Targets

ROCK: 0.5 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 15 mg/mL (48.17 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Thiazovivin can be used to enhance the reprogramming of somatic cells to induced pluripotent stem cells and study its effects on cell adhesion.

Storage

Store at -20ºC.