ROCK inhibitor Y-33075, Purity ≥98%

Synonym: 199433-58-4; Y-33075; Y-39983; Y-39983 free base; Benzamide, 4-(1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, (R)-; Y 39983; 00ALI1GAY2; ROCK inhibitor

CAS Number: 199433-58-4
Compound CID: 9810884

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Y-33075 blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets CaMKII, PKC, and ROCK.

Molecular Weight

280.33

Molecular Formula

C₁₆H₁₆N₄O

Targets

CaMKII: 810 nM; PKC: 420 nM; ROCK: 3.6 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

Y-33075 can be used to investigate the inhibition of Rho-associated protein kinase (ROCK), which plays a role in cytoskeleton organization and cell motility.