ROR inhibitor AGN-242428, Purity ≥98%

Synonym: 1802706-04-2; ROR inhibitor; VTP-43742; VTP 43742; VTP43742; AGN242428; AGN 242428

CAS Number: 1802706-04-2
Compound CID: 91826726

Product Size

1 mg; 2 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AGN-242428 targets and inhibits the activity of the RAR-related orphan receptors, which are nuclear receptors involved in the regulation of various biological processes including immune response, circadian rhythm, and metabolism. It targets RORγt, and RORγt.

Molecular Weight

552.65

Molecular Formula

C₂₇H₃₅F₃N₄O₃S

Targets

RORγt: 3.5 nM (Ki); RORγt: 17 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

AGN-242428 is utilized in research to inhibit ROR receptors, with potential applications in treating autoimmune diseases and inflammatory disorders.