Rotundine

Synonym: 483-14-7; (-)-Tetrahydropalmatine; Gindarine; Caseanine; Hyndarine

CAS Number: 483-14-7
Compound CID: 72301

Product Size

25 mg; 50 mg; 100 mg; 250 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Rotundine, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1A, D1 receptor, D2 receptor, and D3 receptor.

Molecular Weight

355.43

Molecular Formula

C₂₁H₂₅NO₄

Targets

5-HT1A: 347 nM; D1 receptor: 166 nM; D2 receptor: 1.47 μM; D3 receptor: 3.25 μM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 8 mg/mL (22.5 mM); Water: insoluble; Ethanol: insoluble

Applications

Rotundine can be used as a calcium channel blocker.