RS 127445 HCl

Synonym: 199864-86-3; 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine hydrochloride

CAS Number: 199864-86-3
Compound CID: 9905058

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

RS 127445 HCl inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT2A receptor, 5-HT2B receptor, 5-HT2C receptor, 5-HT3 receptor, 5-HT5 receptor, 5-HT6 receptor, and sPLA2.

Molecular Weight

317.79

Molecular Formula

C₁₇H₁₇ClFN₃

Targets

5-HT2A receptor: 6.3 (pKi); 5-HT2B receptor: 9.5 (pKi); 5-HT2C receptor: 6.4 (pKi); 5-HT3 receptor: <6 (pKi); 5-HT5 receptor: <6 (pKi); 5-HT6 receptor: <6 (pKi); sPLA2: 5.5 (pKi)

Form

Lyophilized powder

Purity

>98%

Applications

RS 127445 HCl can be used for its ability to reduce pulmonary vascular resistance and improve blood flow in the lungs.