RSK inhibitor BI-D1870, Purity ≥98%

Synonym: 501437-28-1; BI-D1870; 2-((3,5-Difluoro-4-hydroxyphenyl)amino)-8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6(5H)-one; BI-D 1870; 2-(3,5-Difluoro-4-hydroxyanilino)-5,7-dimethyl-8-(3-methylbutyl)-7H-pteridin-6-one; RSK inhibitor

CAS Number: 501437-28-1
Compound CID: 25023738

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BI-D1870, soluble in DMSO and insoluble in ethanol and water, attenuates the activity of kinases involved in cell growth, survival, and proliferation, which can be utilized to inhibit tumor progression. It targets RSK1, RSK2, RSK3, and RSK4.

Molecular Weight

391.41

Molecular Formula

C₁₉H₂₃F₂N₅O₂

Targets

RSK1; RSK2; RSK3; RSK4

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 71 mg/mL (181.39 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

BI-D1870 can be employed to study its effects on RSK kinase activity and downstream signaling events in cancer.