RSK inhibitor LJH685, Purity ≥98%

Synonym: 1627710-50-2; LJH 685; LJH-685; RSK inhibitor

CAS Number: 1627710-50-2
Compound CID: 73010393

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LJH685, soluble in DMSO and ethanol and insoluble in water, attenuates the activity of kinases involved in cell growth, survival, and proliferation, which can be utilized to inhibit tumor progression. It targets RSK1, RSK2, and RSK3.

Molecular Weight

381.42

Molecular Formula

C₂₂H₂₁F₂N₃O

Targets

RSK1: 6 nM; RSK2: 5 nM; RSK3: 4 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 66 mg/mL (173.03 mM); Water: Insoluble; Ethanol: 17 mg/mL (44.57 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

LJH685 can be used to investigate its selective inhibition of AKT signaling pathways in cancer research.