Properties
Description
LJI308, soluble in warmed DMSO and insoluble in water and ethanol, attenuates the activity of kinases involved in cell growth, survival, and proliferation, which can be utilized to inhibit tumor progression. It targets RSK1, RSK2, and RSK3.
Molecular Formula
C21H18F2N2O2
Targets
RSK1: 6 nM; RSK2: 4 nM; RSK3: 13 nM
Solubility
Warmed DMSO: 66 mg/mL (179.16 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
LJI308 can be used in studies focusing on specific kinase inhibitory effects in various cellular processes.
