RSK inhibitor LJI308, Purity ≥98%

Synonym: 1627709-94-7; LJI 308; LJI-30; RSK inhibitor

CAS Number: 1627709-94-7
Compound CID: 118704762

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LJI308, soluble in warmed DMSO and insoluble in water and ethanol, attenuates the activity of kinases involved in cell growth, survival, and proliferation, which can be utilized to inhibit tumor progression. It targets RSK1, RSK2, and RSK3.

Molecular Weight

368.38

Molecular Formula

C₂₁H₁₈F₂N₂O₂

Targets

RSK1: 6 nM; RSK2: 4 nM; RSK3: 13 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 66 mg/mL (179.16 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

LJI308 can be used in studies focusing on specific kinase inhibitory effects in various cellular processes.