Properties
Description
Rupatadine Fumarate inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets histamine H1 receptor, and PAFR.
Molecular Formula
C26H26ClN3·C4H4O4
Targets
Histamine H1 receptor: 102 nM (Ki); PAFR: 550 nM (Ki)
Applications
Rupatadine fumarate can be studied for its effect on blocking the activity of dopamine receptors in the brain, which are believed to play a role in the development of psychotic symptoms.