Properties
Description
SB-408124, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets OX1 (membrane), and OX1 (whole cell).
Molecular Formula
C19H18F2N4O
Targets
OX1 (membrane): 27 nM (Ki); OX1 (whole cell): 57 nM (Ki)
Solubility
DMSO: 35 mg/mL (98.2 mM); Water: insoluble; Ethanol: insoluble
Applications
SB-408124 can be used for its ability to target and block the OX1 receptor, which is involved in the regulation of sleep, appetite, energy expenditure, and other physiological processes.
