Properties
Description
SB-408124, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets OX1 (membrane), and OX1 (whole cell).
Molecular Formula
C19H18F2N4O
Targets
OX1 (membrane): 27 nM (Ki); OX1 (whole cell): 57 nM (Ki)
Solubility
DMSO: 35 mg/mL (98.2 mM); Water: insoluble; Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
SB-408124 can be used for its ability to target and block the OX1 receptor, which is involved in the regulation of sleep, appetite, energy expenditure, and other physiological processes.
Storage
Store at -20°C, and keep desiccated.
