Properties
Description
SB-742457, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT6.
Molecular Formula
C19H19N3O2S
Targets
5-HT6: 9.63 (pKi)
Solubility
DMSO: 72 mg/mL (203.7 mM); Water: insoluble; Ethanol: 2 mg/mL (5.65 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
SB-742457 can be studied for its effect on promoting sleep onset and maintenance.
Storage
Store at -20°C, and keep desiccated.
