Properties
Description
SCH 23390 HCl, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT2C receptor, D1 receptor, D5 receptor, and GIRK.
Molecular Formula
C17H18ClNO·HCl
Targets
5-HT2C receptor: 9.3 nM; D1 receptor: 0.2 nM; D5 receptor: 0.3 nM; GIRK: 268 nM
Solubility
DMSO: 62 mg/mL (191.21 mM); Water: 19 mg/mL (58.6 mM); Ethanol: 24 mg/mL
Applications
SCH 23390 HCl can be used for its ability to elucidate the involvement of dopamine D1 receptors in mediating certain behaviors, such as locomotor activity, reward processing, cognition, and mood regulation.
