SD-208

Synonym: 627536-09-8; SD 208; SD208; 2-(5-Chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine

CAS Number: 627536-09-8
PubChem CID: 10316032

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SD-208, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets TGF-βRI (ALK5).

Molecular Weight

352.75

Molecular Formula

C₁₇H₁₀ClFN₆

Targets

TGF-βRI (ALK5): 48 nM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 8 mg/mL (22.68 mM); Water: insoluble; Ethanol: insoluble

Applications

SD-208 can be used for its ability to block the downstream signaling cascade initiated by TGF-β.