Properties
Description
Sennoside B inhibits PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway.
Molecular Formula
C42H38O20
Source
Pods of Cassia angutifolia Vahl.
Form
Bright yellow crystals
Purity
>98%, determined by HPLC.
Solubility
It is insoluble in water, benzene, ether, chloroform, slightly soluble in methanol, diglycol-ether, acetone, dioxane, soluble in aqueous sodium bicarbonate.
Identity
Confirmed by NMR and MS.
Applications
Sennoside B can be used for laxative effect experiments, etc.
