Serine protease inhibitor Alvelestat, Purity ≥98%

Synonym: 848141-11-7; Serine protease inhibitor; AZD9668; AZD 9668; AZD-9668

CAS Number: 848141-11-7
Compound CID: 46861623

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Alvelestat, soluble in DMSO and insoluble in ethanol and water, is a molecule that plays a crucial role in regulating various physiological processes by inhibiting the activity of serine proteases. It targets neutrophil elastase and neutrophil elastase.

Molecular Weight

545.5

Molecular Formula

C₂₅H₂₂F₃N₅O₄S

Targets

Neutrophil elastase: 9.4 nM (Ki); Neutrophil elastase: 12 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 87 mg/mL (159.47 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Alvelestat inhibits neutrophil elastase, relevant in treating diseases like COPD.