Properties
Description
Aprotinin, soluble in DMSO and water, is a molecule that plays a crucial role in regulating various physiological processes by inhibiting the activity of serine proteases. It targets chymotrypsin, kallikrein, thrombin, trypsin, and trypsinogen.
Molecular Formula
C284H43N84O79S7
Targets
Chymotrypsin: 9.5 nM (Ki); kallikrein: 0.8 nM (Ki); Thrombin; Trypsin: 0.06 pM (Ki); trypsinogen: 2 μM (Ki)
Solubility
DMSO: 86 mg/mL (13.2 mM); Water: 86 mg/mL (13.2 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Aprotinin is used to study its inhibitory effects on serine proteases, which are important in coagulation and inflammatory pathways.
