SGLT inhibitor Canagliflozin, Purity ≥98%

Synonym: 842133-18-0; SGLT inhibitor

MDL: MFCD18251436
CAS Number: 842133-18-0
Compound CID: 24812758

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Canagliflozin, soluble in DMSO and insoluble in ethanol and water, is a sodium-glucose cotransporter inhibitor, preventing the kidneys from reabsorbing glucose. It targets hSGLT2, mSGLT2, and rSGLT2.

Molecular Weight

444.5

Molecular Formula

C₂₄H₂₅FO₅S

Targets

hSGLT2: 4.4 nM; mSGLT2: 2 nM; rSGLT2: 3.7 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 79 mg/mL (177.71 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Canagliflozin is utilized as an SGLT inhibitor in diabetes research to study its effect on glucose reabsorption and control of blood sugar levels.