Properties
Description
Shikonin, a potent and specific Pyruvate kinase M2 inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), Chinese herbal medicine with various biological activities.
Molecular Formula
C16H16O5
Source
The root of Lithosperraum erythrorhizon Sieb. et Zucc.
Form
Purple flaky crystal or crystalline powder
Purity
>98%, determined by HPLC.
Solubility
It is insoluble in water, soluble in ethanol, organic solvents and vegetable oils. It is easily soluble in alkali solution and precipitates out when it encounters acid.
Identity
Confirmed by NMR and MS.
Applications
Shikonin can be used in the research of acute icteric or anicteric hepatitis, chronic hepatitis, and flat warts, etc.
