Properties
Description
3-TYP, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1, SIRT2, and SIRT3.
Targets
SIRT1: 88 nM; SIRT2: 92 nM; SIRT3: 16 nM
Solubility
DMSO: 25 mg/mL (171.05 mM); Water: Insoluble; Ethanol: 25 mg/mL (171.05 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
3-TYP serves in research aiming to elucidate the role of SIRT3 in cellular metabolism by inhibiting its activity.
