Sirtuins inhibitor AGK2, Purity ≥98%

Synonym: 304896-28-4; AGK 2; Sirtuins inhibitor

CAS Number: 304896-28-4
Compound CID: 2130404

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AGK2, soluble in warmed DMSO and insoluble in water and ethanol, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT2.

Molecular Weight

434.27

Molecular Formula

C₂₃H₁₃Cl₂N₃O₂

Targets

SIRT2: 3.5 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 10 mg/mL (23.02 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

AGK2 is utilized to study neuroprotection by inhibiting SIRT2, impacting microtubule stability.