Sirtuins inhibitor Cambinol, Purity ≥98%

Synonym: 14513-15-6; Cambinol; NSC-112546; NSC112546; Sirtuins inhibitor

CAS Number: 14513-15-6
Compound CID: 3246390

Product Size

10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Cambinol, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1 and SIRT2.

Molecular Weight

360.43

Molecular Formula

C₂₁H₁₆N₂O₂S

Targets

SIRT1: 56 μM; SIRT2: 59 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 19 mg/mL (52.71 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Cambinol is used to examine the role of SIRT1 and SIRT2 in cancer and aging by inhibiting these enzymes.

Storage

Store at -20ºC.