Properties
Description
EX 527 is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1.
Molecular Formula
C13H13ClN2O
Solubility
Water: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
EX 527 is widely used to study SIRT1 function in metabolism, cancer, and aging by acting as a selective inhibitor.