Sirtuins inhibitor Inauhzin, Purity ≥98%

Synonym: 309271-94-1; Inauhzin; 2-((5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-1-(10H-phenothiazin-10-yl)butan-1-one; CHEMBL4787472; 1-Phenothiazin-10-yl-2-(9H-1,3,4,9-tetraaza-fluoren-2-ylsufanyl)-butan-1-one (Inauhzin); Sirtuins inhibitor

CAS Number: 309271-94-1
Compound CID: 5494506

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Inauhzin, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance.

Molecular Weight

469.58

Molecular Formula

C₂₅H₁₉N₅OS₂

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 82 mg/mL (174.62 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Inauhzin is used to investigate p53 regulation by inhibiting SIRT1 and modulating p53 acetylation.

Storage

Store at -20ºC.