Sirtuins inhibitor OSS-128167, Purity ≥98%

Synonym: 887686-02-4; OSS128167; OSS 128167; SIRT6-IN-1; Sirtuins inhibitor

CAS Number: 887686-02-4
Compound CID: 6496840

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

OSS-128167, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1, SIRT2, and SIRT6.

Molecular Weight

366.33

Molecular Formula

C₁₉H₁₄N₂O₆

Targets

SIRT1: 1578 μM; SIRT2: 751 μM; SIRT6: 89 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 68 mg/mL (185.62 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

OSS-128167 is employed in cancer research to inhibit SIRT2 and investigate its impact on tumor growth.

Storage

Store at -20ºC.