Sirtuins inhibitor PROTAC Sirt2 degrader-1, Purity ≥98%

Synonym: 2098487-75-1; PROTAC Sirt2 Degrader-1; Sirt2-PROTAC-1; CHEMBL4225467; 2-((4,6-Dimethylpyrimidin-2-yl)thio)-N-(5-(3-((1-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)acetamide; Sirtuins inhibitor

CAS Number: 2098487-75-1
Compound CID: 135397670

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PROTAC Sirt2 degrader-1 is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT2.

Molecular Weight

852.94

Molecular Formula

C₄₀H₄₀N₁₀O₈S₂

Targets

SIRT2: 0.25 μM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PROTAC Sirt2 degrader-1 is used to study targeted protein degradation of SIRT2, providing insights into PROTAC technology.

Storage

Store at -20ºC.