Sirtuins inhibitor Salermide, Purity ≥98%

Synonym: 1105698-15-4; Salermide; CHEMBL597845; N-{3-[(2-Hydroxy-naphthalen-1-ylmethylene)-amino]-phenyl}-2-phenyl-propionamide; N-[3-[(2-Hydroxynaphthalen-1-yl)methylideneamino]phenyl]-2-phenylpropanamide; Sirtuins inhibitor

CAS Number: 1105698-15-4
Compound CID: 135659046

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Salermide is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1 and SIRT2.

Molecular Weight

394.47

Molecular Formula

C₂₆H₂₂N₂O₂

Targets

SIRT1; SIRT2

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 75 mg/mL (190.13 mM); Water: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Salermide is used to explore the inhibition of SIRT1 and SIRT2, affecting cancer cell proliferation and survival.