Sirtuins inhibitor Salermide, Purity ≥98%

Synonym: 1105698-15-4; Salermide; CHEMBL597845; N-{3-[(2-Hydroxy-naphthalen-1-ylmethylene)-amino]-phenyl}-2-phenyl-propionamide; N-[3-[(2-Hydroxynaphthalen-1-yl)methylideneamino]phenyl]-2-phenylpropanamide; Sirtuins inhibitor

CAS Number: 1105698-15-4
Compound CID: 135659046

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Salermide is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1 and SIRT2.

Molecular Weight

394.47

Molecular Formula

C₂₆H₂₂N₂O₂

Targets

SIRT1; SIRT2

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 75 mg/mL (190.13 mM); Water: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Salermide is used to explore the inhibition of SIRT1 and SIRT2, affecting cancer cell proliferation and survival.

Storage

Store at -20ºC.