Sirtuins inhibitor SirReal2, Purity ≥98%

Synonym: 709002-46-0; SirReal2; SirReal 2; 2-[(4,6-Dimethylpyrimidin-2-yl)sulfanyl]-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide; 2-((4,6-Dimethylpyrimidin-2-yl)thio)-N-(5-(naphthalen-1-ylmethyl)thiazol-2-yl)acetamide; Sirtuins inhibitor

CAS Number: 709002-46-0
Compound CID: 1096292

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SirReal2, soluble in warmed DMSO and insoluble in water and ethanol, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT2.

Molecular Weight

420.55

Molecular Formula

C₂₂H₂₀N₄OS₂

Targets

SIRT2: 140 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 71 mg/mL (168.82 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SirReal2 is employed to investigate selective SIRT2 inhibition and its potential therapeutic applications.

Storage

Store at -20ºC.