Sirtuins inhibitor SIRT-IN-1, Purity ≥98%

Synonym: 1431411-60-7; SIRT-IN-1; 4-(4-{2-[(2,2-Dimethylpropanoyl)amino]ethyl}piperidin-1-Yl)thieno[3,2-D]pyrimidine-6-Carboxamide; CHEMBL2332055; 4-[4-[2-(2,2-Dimethylpropanoylamino)ethyl]piperidin-1-yl]thieno[3,2-d]pyrimidine-6-carboxamide; Sirtuins inhibitor

CAS Number: 1431411-60-7
Compound CID: 71304814

Product Size

1 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SIRT-IN-1 is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1, SIRT2, and SIRT3.

Molecular Weight

389.52

Molecular Formula

C₁₉H₂₇N₅O₂S

Targets

SIRT1: 15 nM; SIRT2: 10 nM; SIRT3: 33 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SIRT-IN-1 is researched for its inhibitory effects on SIRT1 and SIRT2, aiding in the study of their biological roles.

Storage

Store at -20ºC.