Sirtuins inhibitor SIRT-IN-2, Purity ≥98%

Synonym: 1431411-66-3; SIRT-IN-2; 4-(4-{2-[(Methylsulfonyl)amino]ethyl}piperidin-1-Yl)thieno[3,2-D]pyrimidine-6-Carboxamide; CHEMBL2338810; 4-[4-[2-(Methanesulfonamido)ethyl]piperidin-1-yl]thieno[3,2-d]pyrimidine-6-carboxamide; Sirtuins inhibitor

CAS Number: 1431411-66-3
Compound CID: 71304815

Product Size

1 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SIRT-IN-2 is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1, SIRT2, and SIRT3.

Molecular Weight

383.49

Molecular Formula

C₁₅H₂₁N₅O₃S₂

Targets

SIRT1: 4 nM; SIRT2: 1 nM; SIRT3: 7 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

SIRT-IN-2 is used to selectively inhibit SIRT1, exploring its role in various cellular processes.