Sirtuins inhibitor SRT 1460, Purity ≥98%

Synonym: 925432-73-1; SRT-1460; SRT1460; Sirtuins inhibitor

CAS Number: 925432-73-1
Compound CID: 24180124

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SRT 1460, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1.

Molecular Weight

507.6

Molecular Formula

C₂₆H₂₉N₅O₄S

Targets

SIRT1: 2.9 μM (EC1.5)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 20 mg/mL (39.4 mM); Water: Insoluble; Ethanol: 1 mg/mL (1.97 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

SRT 1460 is a SIRT1 activator used to explore its role in metabolism and longevity.