Sirtuins inhibitor SRT 2183, Purity ≥98%

Synonym: 1001908-89-9; SRT2183; SRT-2183; Sirtuins inhibitor

CAS Number: 1001908-89-9
Compound CID: 24180126

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SRT 2183, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1.

Molecular Weight

468.57

Molecular Formula

C₂₇H₂₄N₄O₂S

Targets

SIRT1: 0.36 μM (EC1.5)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 86 mg/mL (183.53 mM); Water: Insoluble; Ethanol: 3 mg/mL (6.4 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SRT 2183 is researched as a SIRT1 activator, addressing its effects on metabolic regulation and aging.

Storage

Store at -20ºC.