Properties
Description
SRT1720 HCl, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT1.
Molecular Formula
C25H23N7OS.HCl
Targets
SIRT1: 0.16 μM (EC50)
Solubility
DMSO: 34 mg/mL (67.19 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
SRT1720 HCl is used in studies on SIRT1 activation to understand its therapeutic potential in metabolic disorders.