Properties
Description
UBCS039, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT6.
Molecular Formula
C16H13N3
Targets
SIRT6: 38 μM (EC50)
Solubility
DMSO: 42 mg/mL (169.83 mM); Water: Insoluble; Ethanol: 14 mg/mL (56.61 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
UBCS039 is used in research to inhibit SUMO E2 enzyme, relevant in studying SUMOylation processes.
