Sirtuins inhibitor UBCS039, Purity ≥98%

Synonym: 358721-70-7; UBCS 039; UBCS-039; Sirtuins inhibitor

CAS Number: 358721-70-7
Compound CID: 2803797

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

UBCS039, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets SIRT6.

Molecular Weight

247.29

Molecular Formula

C₁₆H₁₃N₃

Targets

SIRT6: 38 μM (EC₅₀)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 42 mg/mL (169.83 mM); Water: Insoluble; Ethanol: 14 mg/mL (56.61 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

UBCS039 is used in research to inhibit SUMO E2 enzyme, relevant in studying SUMOylation processes.