Properties
Description
SIS3, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets Smad3.
Molecular Formula
C28H27N3O3·HCl
Solubility
DMSO: 92 mg/mL (187.76 mM); Water: insoluble; Ethanol: 23 mg/mL (46.94 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
SIS3 can be used in studies aimed at understanding the mechanisms underlying fibrosis development and progression.
Storage
Store at -20℃, and keep desiccated.
