Properties
Description
SIS3, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets Smad3.
Molecular Formula
C28H27N3O3·HCl
Solubility
DMSO: 92 mg/mL (187.76 mM); Water: insoluble; Ethanol: 23 mg/mL (46.94 mM)
Applications
SIS3 can be used in studies aimed at understanding the mechanisms underlying fibrosis development and progression.
