Sisomicin Sulfate Analysis Service

Your Satisfaction in Sisomicin Sulfate Analysis Is Our Commitment

Sisomicin sulfate is an aminoglycoside antibiotic that exhibits potent antibacterial activity. It is primarily indicated for diverse infections caused by gram-negative bacteria, particularly Pseudomonas, Escherichia coli, Klebsiella, and Shigella. This class of medications exerts its effect by inhibiting bacterial protein synthesis, thereby impeding their growth and replication. Administration via injection is typically employed to manage severe systemic infections. CD BioGlyco offers comprehensive sisomicin sulfate Pharmaceutical Analysis Services, encompassing a wide range of professional solutions.

Firstly, we use chemical methodologies to analyze sisomicin sulfate. Chemical analysis serves as a means to ascertain crucial information about its chemical composition, structure, and purity. For instance, mass spectrometry is utilized for the determination of its relative molecular mass and characterization of fragment ions. Additionally, nuclear magnetic resonance (NMR) techniques are employed to provide insights into the interconnectivity between atoms within the compound.
In addition, chromatography is utilized for qualitative and quantitative analysis of sisomicin sulfate. High-performance liquid chromatography (HPLC) is one of the methods we commonly utilize, enabling rapid and accurate determination of the quantity of sisomicin sulfate in samples.
We employ biological methods to investigate the interaction between drugs and bacteria or other microorganisms, as well as their inhibitory effects, through in vivo or in vitro experiments. Additionally, we assist in evaluating the kinetic processes of drug absorption, metabolism, and excretion within the human body while exploring potential side effects and toxic reactions.

Fig.1 Sisomicin sulfate analysis service. (CD BioGlyco)

Publication Data

Technology: HPLC with pulsed amperometric detection (HPLC-PAD)

Journal: Chinese Pharmaceutical Journal

IF: 0.33

Published: 2017

Results: This article compares the substance analysis methods of sisomicin sulfate injection, in which the HPLC-PAD method and gas chromatography are used. The advantages and disadvantages of these two methods are compared. The HPLC-PAD method has the advantages of high sensitivity, high accuracy, and good reproducibility, but it needs to use expensive instruments and reagents, while the gas chromatography method has the advantages of simple operation and good separation effect, but the sensitivity is low. The stability of sisomicin sulfate injection is affected by time, temperature, and humidity. The accelerated test results showed that different times, temperatures, and humidity had certain effects on the single and total impurities of the relevant substances in the three manufacturers. This shows that different formulations and production processes have certain effects on the stability of impurities in the preparation.

Fig.2 Chemical structural formula for sisomicin sulfate and related substances. (Huang, et al., 2017)

Advantages

CD BioGlyco has established a diverse network of collaborative relationships with various organizations, and partners to offer an extensive range of integrated analytical services and cater to clients' requirements for additional testing and validation.
We provide customizable service solutions to assist clients in achieving budget-friendly yet high-quality analytical outcomes.
We cater to the urgent requirements of the projects by enhancing analytical procedures and streamlining operations, reducing the duration of analysis cycles, and promptly delivering analytical outcomes.

Over multiple years, CD BioGlyco has consistently achieved outstanding outcomes through the utilization of cutting-edge technologies in pharmaceutical analysis. We trust that our sisomicin sulfate analysis service will be instrumental in facilitating your research endeavors. If you are interested in our service, please feel free to contact us.

Reference

Huang, C.Q. Comparison of analytical methods for related substances of sisomicin sulfate injection. Chinese Pharmaceutical Journal. 2017, 1780-1785.

This service is for Research Use Only, not intended for any clinical use.