Sitaxsentan sodium

Synonym: 210421-74-2; TBC-11251NA

CAS Number: 210421-74-2
Compound CID: 11477084

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Sitaxsentan sodium (TBC-11251) inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets ET-A, and ET-A.

Molecular Weight

476.89

Molecular Formula

C₁₈H₁₄ClN₂NaO₆S₂

Targets

ET-A: 1.4 nM; ET-A: 0.43 nM (Ki)

Form

Lyophilized powder

Purity

>98%

Applications

Sitaxsentan sodium (TBC-11251) can be used to block the binding of endothelin to ETA receptors, thus inhibiting the vasoconstrictive and proliferative effects of endothelin.