Properties
Description
A 803467, soluble in DMSO and ethanol and insoluble in water, blocks sodium channels, affecting the action potential propagation in neurons and muscle cells, crucial for neurological and muscular function. It targets Na(V1.8) channel.
Molecular Formula
C19H16ClNO4
Targets
Na (V1.8) channel: 8 nM
Solubility
DMSO: 64 mg/mL (178.87 mM); Water: Insoluble; Ethanol: 10 mg/mL (27.95 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
A 803467 is a sodium channel inhibitor investigated for its potential to block specific neuronal Na+ channels related to pain signaling.