Properties
Description
GNE-616 blocks sodium channels, affecting the action potential propagation in neurons and muscle cells, crucial for neurological and muscular function. It targets hNav1.7 and hNav1.7.
Molecular Formula
C24H23F4N5O3S
Targets
hNav1.7: 0.79 nM (Ki); hNav1.7: 0.38 nM (Kd)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GNE-616 is a sodium channel inhibitor used in research on cardiac arrhythmias to explore its potential in stabilizing heart rhythm.
