Sodium channel inhibitor ICA-121431, Purity ≥98%

Synonym: 313254-51-2; Sodium channel inhibitor; ICA 121431; ICA121431

MDL: MFCD00992334
CAS Number: 313254-51-2
Compound CID: 998021

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ICA-121431 blocks sodium channels, affecting the action potential propagation in neurons and muscle cells, crucial for neurological and muscular function. It targets hNav1.1, hNav1.3, hNav1.4, hNav1.5, hNav1.6, and hNav1.8.

Molecular Weight

449.55

Molecular Formula

C₂₃H₁₉N₃O₃S₂

Targets

hNav1.1: 13 nM; hNav1.3: 23 nM; hNav1.4: 240 nM; hNav1.5: >10 μM; hNav1.6: >10 μM; hNav1.8: >10 μM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

ICA-121431 blocks sodium channels and is used to investigate neuronal excitability and cardiac arrhythmias.